Not to nitpick but to me the title of this post is implying that XXY individuals are born female. Generally they’re born male.
What the comment is referring to is likely Swyer Syndrome, where the individual has an XY configuration but a dysfunctional gene in the sex-determining region of the Y chromosome. This means the embryo develops female anatomy and the resulting children tend to identify female, but they lack functional gonadal tissue. It’s estimated to occur at a rate of about 1 in a 100,000 females.
By the by, treatment for these individuals usually involves removing the dysfunctional gonadal tissue as it often becomes cancerous (which often gets misunderstood as “gender reassignment surgery”) and supplemental hormone replacement therapy. They would be affected too by any bans on hormone administration to kids often connected with trans people. One of the reasons why blanket bans should be a no-go regardless of how you feel about any other trans issue.
I think we can safely say that is nitpicking, but it’s informative and correct so I’m all for it!
From my biology lessons 20 years ago, I thought I was taught that it was the presence of a second X chromosome that made a person genetically female, but I could definitely be misremembering. Either way, XXY individuals are usually born male, and Dr Genetics Federation was likely talking about sawyer syndrome (or so google tells me). Thanks for the correction!
Not in humans, no! While in some animals sex determination is purely about X dosage (Drosophila), in humans the Y chromosome is actually sex-determining. In females the second X chromosome actually gets inactivated as a means of gene dosage compensation.
TIL, thanks!
Is it still considered HRT if you’re supplementing additional hormones?
Yes. Though I’d point out that HRT covers a much broader range of pathologies than what the current media landscape covers.
As far as I understand, in the original etymology, “replacement” in HRT referred to the fact that the hormone source is coming externally to buoy up a diminished supply in the body. It’s not (necessarily) referring to “displacement” of a hormone that’s already there. More like this usage: when you run out of milk, you go to the store to replace it.
Technically menopausal hormone therapy is HRT, for example. Testosterone replacement in males with low circulating levels is another. Nowadays the usage is definitely shifting, though, and clearly it has a different colloquial meaning.
I decided to Google it just to be safe
And yes he is lmao
And 5 time finalist of the Eureka Prize - which sounds impressive even if I’ve never heard of it!
Just saying the word eureka is exciting
Not if you live in north west California, then it’s just a town name.
Isn’t it latin for ‘fetch me my towel’?
According to Wikipedia
“Eureka” comes from the Ancient Greek word εὕρηκα heúrēka, meaning “I have found (it)”, which is the first person singular perfect indicative active of the verb εὑρίσκω heurískō “I find”. It is closely related to heuristic, which refers to experience-based techniques for problem-solving, learning, and discovery.
I was having a civil and boring discussion with someone on a (non-anonymous) forum once about a highly specific technical thing, and then some random person decides to write something along the lines of “I have nothing to add to this conversation, but I just want to point out that the guy you’re talking to is actually an employee of <well known company> :)”
I don’t know if that guy felt any cringe after posting that, but I sure as hell felt it for him. Neither of us really knew how to respond to that, and it kind of just killed the discussion to avoid that awkwardness.
Sometimes I still think about that guy. Is he still vicariously Pretty Woman’ing people? Did he accomplish some of his life goals? I hope so.
Literally Mansplaining.
/s
Mic drop…
I am curious about the video though
Transphobic BS I believe. But I’m not trawling through fb to find the original.
Being a president of something doesn’t mean crap though.
It does if it’s as prestigious and well known as the International Genetics Federation.
It doesn’t. Administrative work requires different set of skills of knowledge from scientist work.
Well, he has a doctorate and has been cited over 13,000 times. So for this particular institution, it absolutely does.
So he should’ve bragged about citations. Because, once again, being a president of something doesn’t mean shit.
I’m going to make a new club right now and call it the International Institute for Genetic Study and name myself the president.
Is he mixing up people with 3 gonosomes?
Because these are not too rare. It’s one of the more frequent mutations.
But even a person with XXY is a male. Since the male gonosome is considered as a mutation of an X chromosome. Somewhere in the evolution of mammals and other vertebrates (or most likely much earlier) something messed up and created the Y chromosome from an X chromosome. That’s why genetic diseases are usually more frequent in males, since one branch of the X chromosome does not have some backup. It’s simply missing.
So whenever a person has one Y chromosome. It is considered male. The lack of a Y chromosome is considered a female.
This can also be seen in people with genetic disorders, such as three gonosomes. XXX is a female XYY is a male XXY is also a male.
And to everyone’s information: I am for Germany and we do not have two words for sex and gender.
I don’t understand what you English speakers are up to.
They are talking about things like Androgen Insensitively Syndrome where XY people are born with female anatomy. This is because the chromosome dosen’t determine gentials but rather the hormones that chromesome creates. In the case of Androgen Insensitivity the body dosen’t respond to male hormones so develops female gentials despite having male chromesomes because female is the default. Weiredly enough though the gonads are still male.
Could also be refering to Swayer syndrome.
I just wrote a comment above but I believe OP is mixing XXY with what the comment was about, which is likely Swyer Syndrome: XY individuals with female anatomy and gonadal dysgenesis. While they have a Y chromosome, a defective sex-determining gene leads to a failure to sexually differentiate into male gonadal tissue and leads to subsequent loss of downstream sex hormone production.
So I assume such people are identified as females at birth. But if their chromosomes indicate that they are male, what’s the gender then?
I think it’s a male then, right? Because when a defect leads to malformations, it still is a malformation. One that people could probably live very well with.
If male and female are assigned purely based on physical anatomy, does it really matter?
No one in that person’s life would consider them male and doctors would treat them based on their sex characteristics - they may have testes but they wouldn’t be external.
I have never been karyotyped and I’m willing to bet most people haven’t either; your sex is assumed based on your outward appearance even when your genitals are not observable.
I really don’t think that having a Y chromosome makes you male when you literally have a vagina, you know? Especially when you could go your whole life without knowing.
If the SRY gene is broken, they’d still physically develop as female, though potentially with some abnormalities, rather than as male. Even leaving gender identity out of it, sex is still more complicated than
if exists Y; then maleBut If I have a construction plan, and this plan is somewhat flawed, but I start building anyway, then I am still building the planned object, but with flaws?
I don’t want to offend anyone. I myself have a genetic defect, much worse if you ask me, than some sexual genetic defect. I can barely consume any fructose without shitting myself. ¯_(ツ)_/¯
I think if we’re going to use the construction plan metaphor, it would be more accurate to say that the builders didn’t get the message to alter the plans. Like if there was a house plan that was designed so it could be a duplex or a single family home by adding or removing one wall. Both options actually exist in the plans for the house at all times (yes, XX still has the genetic code for male anatomy), the SRY gene isn’t the plans to build male anatomy, that’s stored elsewhere, the SRY gene is more like a text to the builder saying “go with option B”. Except in this case the text failed to send, so the builder defaulted to option A.
So at the end of the day, the builder doesn’t put the wall in and builds a single family home, not a duplex. The owner may have wanted a duplex, but that isn’t what got built. So is it a duplex or not? I would lean towards saying no, but we’re not talking about houses, we’re talking about people, so it should probably just be their call
You had me up to:
And to everyone’s information: I am for Germany and we do not have two words for sex and gender. I don’t understand what you English speakers are up to.
I don’t understand what you mean here? I’m sure biological sex and gender identity are considered separate ideas even in languages without a specific word for them. To my mind a lot of transphobia comes from people not understanding there’s a difference between sex and gender.
As for the XXY, I’m OP and that’s my mistake. I misremembered my biology lessons and thought a second X chromosome made someone biological female, rather than the presence of an Y chromosome making someone male. I replied to someone else explaining my mistake.
I don’t understand what you mean here? I’m sure biological sex and gender identity are considered separate ideas even in languages without a specific word for them.
Some people here in Germany claim so. These people use the English word “gender”, because German doesn’t offer a specific word for that. But I don’t understand why one has to differentiate. I don’t think there is gender identity. Identity is the constitution of my character and my values. Feelings and emotions are not part of character, they are reactions to stimuli.
To my mind a lot of transphobia comes from people not understanding there’s a difference between sex and gender.
But that’s barely comprehensible to me. How could it ever be, if my language does not offer this differentiation. The way we talk strongly affect the way we think. And I am not thinking in categories such as gender and sex. There is just gender (the last sentences sound weird. But I simply cannot translate it)
As for the XXY, I’m OP and that’s my mistake. I misremembered my biology lessons and thought a second X chromosome made someone biological female, rather than the presence of an Y chromosome making someone male. I replied to someone else explaining my mistake.
Alright. Nature is crazy.
We don’t have a word for schadenfreude in English, but trust me, we still experience it.
Identity is the constitution of my character and my values. Feelings and emotions are not part of character, they are reactions to stimuli.
What does that have to do with gender? Just because you think you don’t care about gender, doesn’t mean that society doesn’t, or that gender doesn’t care about you.
Sex: Biological and even then sometimes biology screws up
Gender: Social and sometimes people raised as one gender don’t identify as being that gender
Gender: Social and sometimes people raised as one gender don’t identify as being that gender
But why the word gender then?
Because if it only relates to the way someone was raised, then it is not connected to the sex. The role of a male or the role of a female are very different in other cultures. So gender becomes something extremely vague.
What if I identify my gender to be male? What does that even mean then? Is my gender then what European men are like? What kind of European man? Or a Muslim man? Maybe an ultra radical Indian man who would burn his wife?
The role of a man and a woman is usually a purely social construct. Why would I identify with such a construct? It’s so vague. And what use does gender identity have? We humans use such terms usually to classify the properties of a human. But the gender term seems to be a bad classification standard. Classification must be something specific. But this gender term is not very specific.
This English stuff makes me go mad. It makes me go mad. Maybe for context: the German word “Geschlecht” is also not the most precise. It means sex, but in the past it also meant something like old family, like the some old royal family. It is also used genealogically.
If I am a male and I am looking for a mate to make children, then I am not interested in the persons belief, what they believe to be, but their biological properties.
When does gender become relevant?
I have looked up gender studies. Gender studies started to analyse the cultural and social dynamics between the sexes. Also analysing the roles, male and females take in society according to their sex. But the term gender, does that not undermine those studies? Because how can you analyse those dynamics, if gender becomes a term so loose?
But why the word gender then?Because words have a meaning and you don’t seem to understand the difference between sex and gender so I explained it to you in the simplest way possible. If you want to argue that gender doesn’t exist then I can refer you to tons of videos from people much more knowledgeable than you and me on that subject.
It’s funny that you say “German is a precise language” and you’re mad that in English there’s a word to distinguish between two separate concepts… Are you somehow trying to argue that German is a superior language instead of admitting that maybe it doesn’t cover every possibilities? Wait until you learn about Japanese and Mandarin with their words for abstract concepts!
Why would I identify with such a construct?You don’t live in society?
If I am a male and I am looking for a mate to make children, then I am not interested in the persons belief, what they believe to be, but their biological properties.Oh so then you don’t mind if your mate looks like him or do you think it might be relevant to speak about gender now that you’re thinking about forming a family with that person? This part of your text also makes you sound a lot like you believe in eugenics… Trying to pass your genes based on the how good the other people is biologically and nothing else… I’ll leave it at that…
I don’t know where you found your definition of gender study but it’s exactly what it says, women study has been a thing for ages, nothing unusual about broadening that field to encompassate more than just women and it just so happens that some people don’t fit in what is men or women gender expectations.
You’re stuck on the fact that genders vary from place to place… As if everything else is the same no matter where you look in the world? A person raised male but identifying as female might have been two spirit (a gender older than the society you live in by the way) had they been raised in a traditional first Nation family, but that’s not their reality and as such they make their situation make sense in the context they live in.
Just because your language doesn’t have a word for it doesn’t mean people don’t experience it, it just means your language needs to evolve. If the word for depression doesn’t exist in a language then do you think depression doesn’t exist for the people who speak it?
As an English speaker, trust me you don’t wanna know. Don’t dive into it
Well, since there is just one word in German for sex and gender, it’s the same thing here, some people try to use the English word gender (untranslated) here.
But I simply don’t understand why this is needed. It’s getting so mixed up and complicated, but at the same time it barely has any relevance. Because what does it add to society, dialogue or communication? German is a very precise language, and I don’t understand why some people try to soften it up with the English term of gender. It’s so weird.
I’m pretty sure alot of people use it interchangeably to mean the same thing. But I think over the years, gender has become more of a “social” word and Sex as more of a “biological” word. I say Gender instead of sex when talking about someone’s biology. A bit confusing honestly for non-native English speakers
Yes, it’s confusing. I think I somewhat have an understanding of what the term “gender” refers to, it at the same time it is so untranscribable and somewhat extremely vague.
Why? It’s the same thing as race.
No it cannot be.
Race is a biologically misleading term. There is just one human race alive on this planet and it’s called Homo sapiens sapiens.
What English speakers are referring to as race is actually ethnicity.
The genetic variations between humans from different continents is far too little to make out different races. There are no clear borders between one “race” to another.
You missed the point. Race is a social construct, as is gender
